徐加俊
一、个人简介
徐加俊，吉林大学博士（2020-2023），于2023年10月入职河北大学化学与材料科学学院，现为河北大学校聘副教授，河北省教育厅青年拔尖人才，硕士研究生导师。主要从事近红外功能/靶向性分子探针的开发及其一体化精准诊疗研究。迄今为止，在Nat. Commun.；Sci. Adv.；Adv. Mater.；Nano Lett.；Adv. Sci.；Chinese Chem. Lett.；Adv. Healthc. Mater.；Theranostics; Chem. Eng. J. 等知名学术期刊上发表论文30余篇，授权发明专利2项，获吉林省自然科学二等奖1项（2/3），吉林省自然科学三等奖1项（5/5）。其中以第一/通讯作者身份发表SCI论文15篇, H 因子16，并主持科研基金项目6项。
联系方式：E-mail: jjxu_bio@hbu.edu.cn ；jjxu_bio@163.com
欢迎每一位对化学-医学交叉学科感兴趣的研究生和本科生加入本课题组交流和学习！
二、研究方向
主要围绕近红外分子影像及其一体化精准诊疗，拟开发多种集生物成像诊断和精准治疗于一体的新型分子/纳米诊疗平台，对多种临床疾病模型进行早期筛查和精准原位治疗，并实时监测治疗效果和预后。
1. 设计合成近红外功能/靶向性探针
2. 开发多种宏观/微观载药体系(凝胶/纳米粒子）
3. 对临床相关疾病模型进行活体、离体的可视化诊疗研究
三、代表性论文
(15). Zijian Jiang, Yijing Du, Zetao Dang, Tongze Liu, Mengyuan Liu, Sun Bin, Feiran Zhang*, Jiajun Xu*, Shoujun Zhu*. Biomimetic NIR-II fluorescent probe from covalent encapsulation enables high-performance NIR-II bioimaging, Chinese Chemical Letters, 2026, 37, 111351.
(14). Jiajun Xu*, Yijing Du, Ningning Zhu, Jia Li*, Yuewei Zhang, Ding Zhou*, Shoujun Zhu*. NIR-II fluorescent protein created by in situ albumin‐tagging for sensitive and specific imaging of blood-brain barrier disruption, Advanced Science, 2025, 12, 2500443.
(13). Liang Sun, Baiqiang Luo, Zequn Sun, Xiuyan Ren*, Jiajun Xu*, Anti-swelling hydrogel with three-dimensional print for underwater communication, Materials Today Communications, 2025, 46, 112605.
(12). Jia Si, Xingtong Zhu, Yun Wei, Zhenyu Li*, Jiajun Xu*, Xiuyan Ren*, A Shape-Memory and Durable Transparent Polyacrylate Film Integrated by Soft-Rigid Chains, Chemistry-A European Journal, 2024, e202404154.
(11). Jiajun Xu, Ningning Zhu, Yijing Du, Tianyang Han, Xue Zheng, Jia Li, Shoujun Zhu*. Biomimetic NIR-II fluorescent proteins created from chemogenic protein-seeking dyes for multicolor deep-tissue bioimaging. Nature Communications, 2024, 15, 2845.（Highly Cited Papers）
(10). Ningning Zhu+, Jiajun Xu+, Qi Su, Tianyang Han, Ding Zhou*, Yuewei Zhang*, Shoujun Zhu*, Site-specific albumin tagging with NIR-II fluorogenic dye for high-performance and super-stable bioimaging. Theranostics, 2024,14,1860-1872.
(9). Jiajun Xu, Yijing Du, Tianyang Han, Ningning Zhu, Shoujun Zhu*. Protein@cyanine-based NIR-II lymphography enables the supersensitive visualization of lymphedema and tumor lymphatic metastasis. Advanced Healthcare Materials, 2023, 12, 2301051.
(8). Feiran Zhang+, Jiajun Xu+, Chengbin Zhang+, Yin Li, Jiawei Gao, Limei Qu*, Songling Zhang*, Shoujun Zhu*, Junhu Zhang*, Bai Yang. Three-dimensional histological electrophoresis for high-throughput cancer margin detection in multiple types of tumor specimens. Nano Letters. 2023, 23, 7607−7614.
(7). Jiajun Xu,Tianyang Han, Yajun Wang, Feiran Zhang, Mengfei Li, Lang Bai, Xinyu Wang, Bin Sun, Xin Wang, Jianshi Du, Kun Liu, Junhu Zhang, and Shoujun Zhu*. Ultrabright renal-clearable cyanine-protein nanoprobes for high-quality NIR-II angiography and lymphography. Nano Letters. 2022, 22, 7965−7975.
(6). Jiajun Xu, Rining Jin, Xiuyan Ren*, Guanghui Gao*. A wide temperature-tolerant hydrogel electrolyte mediated by phosphoric acid towards flexible supercapacitors. Chemical Engineering Journal, 2021, 413, 127446.
(5). Jiajun Xu, Rining Jin, Xiuyan Ren*, Guanghui Gao*. Fish-inspired anti-icing hydrogel sensors with low temperature adhesion and toughness. Journal of Materials Chemistry A, 2020, 8, 9373–9381.
(4). Jiajun Xu, Rining Jin, Xiuyan Ren*, Guanghui Gao*. Cartilage-inspired hydrogel strain sensors with ultrahigh toughness, good self-recovery and stable anti-swelling properties. Journal of Materials Chemistry A, 2019, 7, 25441–25448.
(3). Jiajun Xu, Guangyu Wang, Yufan Wu, Xiuyan Ren*, Guanghui Gao*. Ultra-stretchable wearable strain and pressure sensors base on adhesive, tough and self-healing hydrogels for human motion monitoring. ACS Applied Materials & Interfaces, 2019, 11, 25613−25623.
(2). Jiajun Xu, Rining Jin, Lijie Duan, Xiuyan Ren*, Guanghui Gao*. Tough, adhesive and conductive polysaccharide hydrogels mediated by ferric solution. Carbohydrate. Polymers, 2019, 211, 1–10.
(1). Jiajun Xu, Xiuyan Ren*, Guanghui Gao. Salt-inactive hydrophobic association hydrogels with fatigue resistant and self-healing properties. Polymer, 2018, 150, 194–203.
四、科研项目
国家自然科学基金青年科学基金项目 (2026-2028年, 主持)
河北大学多学科交叉研究项目 (2026-2028年, 主持)
河北省高等学校科学研究项目-产学研合作专项 (2026-2028年, 参与)
河北省教育厅青年拔尖人才项目 (2025-2027年,主持）
河北省自然科学基金青年基金项目 (2024-2027年,主持）
药物化学与分子诊断教育部重点实验室主任基金项目 (2024-2027年,主持）
河北大学高层次人才科研启动项目 (2023-2027年,主持）
