一、个人简介
张江艳,1986年生于河北省廊坊市,理学博士,副教授,硕士生导师,2015年7月毕业于中国科学院大学化学研究所,同年被引进到河北大学化学与环境科学学院工作。
E-mail:zhangjiangyan@hbu.edu.cn
二、主讲课程及研究方向
1.主讲课程: 仪器分析、分子光谱学、基础仪器分析实验、基础化学分析实验
2.研究方向: (1)体外诊断技术开发;(2)核酸、蛋白质、抗生素等的检测;(3)细菌、细胞的检测与杀伤
课题组学术氛围浓厚、实验设备先进,欢迎加入我们的团队一起开展科学研究。
三、代表性论文
1. Xinrong Yan,Jiangyan Zhang,* Qi Jiang, Dan Jiao, Yongqiang Cheng,* Integration of the Ligase Chain Reaction with the CRISPR-Cas12a System for Homogeneous, Ultrasensitive, and Visual Detection of microRNA,Analytical Chemistry, 2022, 94, 4119-4125.
2.张江艳,严景丽,成永强*, RNA生物标志物体外检测方法研究进展,中国科学:化学,2021,51,1191-1205.
3. Qi Jiang, Xinrong Yan, Dan Jiao,Jiangyan Zhang*, Yonggang Wu*, Yongqiang Cheng*, Polymyxin B-modified conjugated oligomer nanoparticle for targeted identification and enhanced photodynamic antimicrobial therapy,Chemical Communications, 2021, 57, 11244-11247.
4. Jinying Liu,Jiangyan Zhang*, Meiqi Chen, Dehui Qiu, Xuechong Lv, Qi Jiang, Yongqiang Cheng*, Integration of magnetic separation and real-time ligation chain reaction for detection of uracil-DNA glycosylase.Analytical and Bioanalytical Chemistry, 2021, 413, 255-261.
5. Qi Jiang, Fangjie E, Jiangxiao Tian, Jiangtao Yang,Jiangyan Zhang*, Yongqiang Cheng*, Light-Excited Antibiotics for Potentiating Bacterial Killing via Reactive Oxygen Species Generation.ACS Applied Materials & Interfaces,2020, 12, 16150-16158.
6. Lijuan Dong, Xuange Zhang, Yaru Li, Fangjie E,Jiangyan Zhang*, Yongqiang Cheng*, Highly Sensitive Detection of Uracil-DNA Glycosylase Activity Based on Self-Initiating Multiple Rolling Circle Amplification.ACS omega, 2019,4(2), 3881-3886.
7. Lingyun Du,Jiangyan Zhang*, Xuange Zhang, Yaru Li, Qi Jiang, Yonggang Wu*, Yongqiang Cheng, Multifunctional Oligonucleotide-Functionalized Conjugated Oligomer Nanoparticles for Targeted Cancer Cell Imaging and Therapy.ACS Applied Bio Materials, 2019, 2(3), 1340-1347.
8.Jiangyan Zhang, Likun Zhao, Lijuan Dong, Xueyu Nie, Yongqiang Cheng*, Integration of T7 Exonuclease-triggered Amplification and Cationic Conjugated Polymer Biosensing for Highly Sensitive Detection of MicroRNA.Talanta, 2018, 1, 475-479.
9. YaCui Liu,Jiangyan Zhang*, Jingxiao Tian, Xiaofei Fan, Hao Geng, Yongqiang Cheng*, Multiplex Detection of microRNAs by Combining Molecular Beacon Probes with T7 Exonuclease-assisted Cyclic Amplification Reaction.Analytical and Bioanalytical Chemistry, 2017, 409(1): 107-114.
10. Likun Zhao,Jiangyan Zhang*, Huiming Xu, Hao Geng, Yongqiang Cheng*, Conjugated Polymers/DNA Hybrid Materials for Protein Inactivation.ACS Applied Materials & Interfaces, 2016, 8(35), 22923-22929.
11. Yingcun Li,Jiangyan Zhang*, Jingjing Zhao, Likun Zhao, Yongqiang Cheng*, Zhengping Li, A simple molecular beacon with duplex-specific nuclease amplification for detection of microRNA.Analyst, 2016, 141(3): 1071-1076.
12.张江艳,袁焕祥,朱春雷,刘礼兵,吕凤婷*,王树*,共轭聚合物在病原微生物识别、成像与杀伤中的应用研究.中国科学:化学,2016,46 (02):153-162.
13.Jiangyan Zhang, Baoling Xing, Jinzhao Song, Feng Zhang, Chenyao Nie, Lian Jiao, Libing Liu, Fengting Lv, Shu Wang*, Associated Analysis of DNA Methylation for Cancer Detection Using CCP-Based FRET Technique.Analytical Chemistry, 2014, 86(1): 346-350.
四、科研项目
1. 基于免疫-环介导等温扩增反应的多模传感平台开发及其在蛋白分析中的应用(项目批准号:236Z2402G),河北省中央引导地方科技发展资金项目(2023-2025年,主持人)
2. 基于连接反应的一步法实时检测microRNA(项目批准号:X2JJ202214),河北大学校长科研基金项目(2023-2025年,主持人)
3. 连接酶链式反应实时多重检测平台的构建及其在 mRNA 结构变异检测中的应用(项目批准号:B2022201017),河北省自然科学基金面上项目(2022-2024年,主持人)
4.基于DNA组装的化学发光共振能量转移介导的靶向光动力疗法研究(项目批准号:21605034),国家自然科学基金项目 (2017-2019年,主持人)
5. 以化学发光为光源的光动力疗法研究(项目批准号:B2017201184),河北省自然科学基金青年项目(2017-2019年,主持人)